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2014-10-22 Imidazo[1,2-a]imidazolin-2-ones available on Ambinter

In order to provide new and original chemical compounds to our customers, Greenpharma/Ambinter has developed innovative synthesis routes with partners. For example, 6(5)-bromo-5(6)-methylimidazo[1,2-a]imidazolin-2-ones are now available in Ambinter catalogue.

You can find more information on the publication (abstract below) in European Journal of Organic Chemistry, 2013, 19, 4146-4155.

New access to Imidazo[1,2-a]imidazolin-2-ones and effective functionalization through Suzuki-Miyaura cross coupling reactions
A new route to 6(5)-bromo-5(6)-methylimidazo[1,2-a]imidazolin-2-ones have been developed. Then, a novel and effective strategy of functionnalization of these scaffolds throught Suzuki-Miyaura cross coupling reactions is reported. Thanks to this methodology, a large panel of boronic acids were easily introduced, giving access to a diversified library of 6(5)-substituted-5(6)-methylimidazo[1,2-a] imidazolin-2-ones.

Click on the link to display the structures of Imidazo[1,2-a]imidazolin-2-ones library.

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